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Generic Name:                   Flavoxate Hydrochloride
Therapeutic Category:  Urinary tract spasmolytic.
Pharmacological Class:  Muscarinic receptor antagonist 
Composition:                      Each blister contains Flavoxate Hydrochloride 200 mg
Pregnancy Category: B
Presentation: Available in the pack size as 10 tablets X 10 strips

What is Uroxate and what is it used for?

Uroxate contains Flavoxate Hydrochloride 200 mg in tablet form. It belongs to a group of medicines which relieve and prevent muscle spasms. It is used to treat muscle spasms of the urinary tract. Uroxate is used in

  • Urinary frequency & incontinence
  • Cytoscopy/surgery
  • Urethrocystitis/urethrotrigonitis
  • Bladder spasms due to catheterisation
  • Urinary urgency
  • Symptomatic relief of dysuria
  • Nocturia
  • Cystitis
  • Urethritis
  • Suprapubic pain
  • Dysuria
  • Prostatitis


How does it work?

Uroxate is a smooth-muscle relaxant. It works by relaxing the muscles in the bladder. Flavoxate helps to reduce leaking of urine, feelings of needing to urinate right away, frequent trips to the bathroom, and bladder pain.


How to take Uroxate?

Children <12 years: Not recommended; safety and efficacy not established

Children ≥12 years: 100-200 mg 6-8 hourly

18 years and older: 200 mg orally 3 to 4 times daily

This medication must be taken orally.




What if you miss a dose?

If you miss a dose do not worry, take the next dose at the usual time. Do not take a double dose to make up for a forgotten tablet.


What to do in case of overdose?

If you accidentally take too many Uroxate tablets, contact your doctor or hospital immediately

What do you need to know before you take Uroxate?

Do not take Uroxate:

  • If you are allergic to flavoxate hydrochloride or any of the other ingredients of this medicine
  • If you are a child younget than 12 years old
  • If you have a gastrointestinal disease that affects the normal passage of food
  • If you have an gastro-intestinal bleeding
  • If you have a muscular inability to swallow
  • If you are not able to completely empty your bladder (urinary retention)
  • If you are being treated for an eye disease called glaucoma
  • If you have a disease which causes general weakness and fatigability of the muscles (myasthenia gravis)


Warning and Precautions

Talk to your doctor or pharmacist before taking Uroxate if you have impaired kidney function.

Uroxate and other medications

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.


Pregnancy and breast-feeding


If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.



The safety of this medicine in lactation has not been established. If you are breast-feeding this medicine is not recommended.




Driving and using machines

Do not drive or operate machinery if you experience somnolence or blurred vision whilst taking Uroxate.


What are the possible side effects?

Uroxate is generally well tolerated, but can potentially cause, vomiting, upset stomach, dry mouth or throat, blurred vision, eye pain, and increased sensitivity of your eyes to light.

Mechanism of action:

Flavoxate Hydrochloride exerts a direct relaxant effect on smooth muscles via phosphodiesterase inhibition, providing relief to a variety of smooth muscle spasms. This counteracts smooth muscle spasms of urinary tract.


Pharmacokinetic properties:

Absorption: Well absorbed from gastrointestinal tract


Protein binding: Approximately 90%


Metabolism: Hepatic (rapid metabolism)


Route of elimination: Urine (50-60%)


Half–life: 2-3 minutes