(+977) 4110791, 01-4110761 info@opl.com.np
Your content goes here. Edit or remove this text inline or in the module Content settings. You can also style every aspect of this content in the module Design settings and even apply custom CSS to this text in the module Advanced settings.

Flavoxate is an anticholinergic with anti-muscarinic effects. Its muscle relaxant properties may be due to a direct action on smooth muscle rather than by antagonizing muscarinic receptors.

Mechanism of Action

UROXATE exerts a direct relaxant effect on smooth muscles via phosphodiesterase inhibition, providing relief to a variety of smooth muscle spasms. This counteracts smooth muscle spasms of urinary tract.


  • Urinary frequency & incontinence*
  • Cytoscopy*/surgery
  • Urethrocystitis*/urethrotrigonitis*
  • Bladder spasms due to catheterisation
  • Urinary urgency
  • Symptomatic relief of dysuria
  • Nocturia*
  • Cystitis
  • Urethritis
  • Suprapubic* pain
  • Dysuria
  • Prostatitis


Route of administration: Oral

Children <12 years: Not recommended; safety and efficacy not established

Children ≥12 years: 100-200 mg PO q6-8hr

18 years and older: 200 mg orally 3 to 4 times daily

Medication to be taken after meals.


Absorption: Well absorbed from gastrointestinal tract.

Protein binding: Approximately 90%

Metabolism: Hepatic (rapid metabolism)

Route of elimination: Urine (50-60%)

Halflife: 2-3 minutes


Adverse Effects

UROXATE is generally well tolerated, but can potentially cause, vomiting, upset stomach, dry mouth or throat, blurred vision, eye pain, and increased sensitivity of your eyes to light.


UROXATE is contraindicated in the following conditions:

  • Obstructive conditions: pyloric or duodenal obstruction, obstructive intestinal lesions or ileus, achalasia, gastro-intestinal hemorrhage and obstructive uropathies of the lower urinary tract.
  • Hypersensitivity to Flavoxate hydrochloride or to any of the excipients of Uroxate.


UROXATE must be used cautiously in:

  • Patients with suspected glaucoma, especially closed angle cases


No data regarding the interactions of Flavoxate (HCl) was found.


Incontinence: Lack of voluntary control over urination or defecation.

Cystoscopy: Procedure that allows your doctor to examine the lining of your bladder and the tube that carries urine out of your body (urethra)

Urethrocystitis/Urethrotrigonitis: Inflammation of the urethra and the bladder; trigone of the bladder

Nocturia: Excessive urination at night.

Suprapubic: Situated, occurring, or performed from above the pubis