|What is Omicox?
Omicox contains Etoricoxib 60 mg, 90 mg, 120 mg Tablets.
|What is it used for?
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute pain conditions
- Acute gouty arthritis
- Postoperative dental surgery pain
|How does it works?
Like any other COX-2 selective inhibitor Etoricoxib selectively inhibits isoform 2 of cyclo-oxigenase enzyme (COX-2), preventing production of prostaglandins (PGs) from arachidonic acid.
|How to take Omicox?
The recommended dose is 30 mg once daily. In some patients with insufficient relief from symptoms, an increased dose of 60 mg once daily may increase efficacy. In the absence of an increase in therapeutic benefit, other therapeutic options should be considered.
The recommended dose is 60 mg once daily. In some patients with insufficient relief from symptoms, an increased dose of 90 mg once daily may increase efficacy. Once the patient is clinically stabilized, down-titration to a 60 mg once daily dose may be appropriate. In the absence of an increase in therapeutic benefit, other therapeutic options should be considered.
The recommended dose is 60 mg once daily. In some patients with insufficient relief from symptoms, an increased dose of 90 mg once daily may increase efficacy. Once the patient is clinically stabilised, down-titration to a 60 mg once daily dose may be appropriate. In the absence of an increase in therapeutic benefit, other therapeutic options should be considered.
Acute gouty arthritis
The recommended dose is 120 mg once daily.
Postoperative dental surgery pain
The recommended dose is 90 mg once daily, limited to a maximum of 3 days.
|What if you miss the dose?
If you forget to take the tablet at your usual time, take it as soon as you remember. Do not take two doses at the same time to make up for a missed dose.
|What to do in case of overdose?
In clinical studies, administration of single doses of etoricoxib up to 500 mg and multiple doses up to 150 mg/day for 21 days did not result in significant toxicity. In the event of overdose, it is reasonable to employ the usual supportive measures, e.g., remove unabsorbed material from the GI tract, employ clinical monitoring, and institute supportive therapy, if required.
|What to you need to know before you take Omicox?
Do not take it
If you are allergic to etoricoxib or any of the other ingredients of this medicine.
If you are allergic to non-steroidal anti-inflammatory drugs (NSAIDs), including acetylsalicylic acid and COX-2 inhibitors.
If you have a current stomach ulcer or bleeding in your stomach or intestines.
If you have serious liver disease.
If you have serious kidney disease.
If you are or could be pregnant or are breast-feeding.
If you are under 16 years of age.
If you have inflammatory bowel disease, such as Crohn’s Disease, ulcerative colitis, or colitis.
If you have high blood pressure that has not been controlled by treatment (check with your doctor or nurse if you are not sure whether your blood pressure is adequately controlled).
If your doctor has diagnosed you with heart problems including heart failure (moderate or severe types), angina (chest pain).
If you have had a heart attack, bypass surgery, peripheral arterial disease (poor circulation in legs or feet due to narrow or blocked arteries).
If you have had any kind of stroke (including mini-stroke, transient ischemic attack or TIA). Etoricoxib may slightly increase your risk of heart attack and stroke and this is why it should not be used in those who have already had heart problems or stroke.
Warning and Precautions
Talk to your doctor or pharmacist before taking etoricoxib if:
You have a history of stomach bleeding or ulcers.
You are dehydrated, for example by a prolonged bout of vomiting or diarrhoea.
You have swelling due to fluid retention.
You have a history of heart failure, or any other form of heart disease.
You have a history of high blood pressure. Etoricoxib can increase blood pressure in some people, especially in high doses, and your doctor will want to check your blood pressure from time to time.
You have any history of liver or kidney disease.
You are being treated for an infection. Etoricoxib can mask or hide a fever, which is a sign of infection.
You have diabetes, high cholesterol, or are a smoker. These can increase your risk of heart disease.
You are a woman trying to become pregnant.
You are over 65 years of age.
Etoricoxib must not be taken during pregnancy. If you are pregnant or think you may be pregnant or are planning to have a baby, do not take the tablets. If you become pregnant, stop taking the tablets and consult your doctor.
Consult your doctor if you are unsure or need more advice.
It is not known if etoricoxib is excreted in human milk. If you are breast-feeding, or planning to breast-feed, consult your doctor before taking etoricoxib. If you are taking etoricoxib, you must not breast-feed.
|Driving and using machines
Dizziness and sleepiness have been reported in some patients taking etoricoxib.
Do not drive if you experience dizziness or sleepiness.
Do not use any tools or machines if you experience dizziness or sleepiness.
|What are the possible side effects?
Very common (may affect more than 1 in 10 people)
– Stomach pain.
Common (may affect up to 1 in 10 people)
Dry socket (inflammation and pain after a tooth extraction),
Swelling of the legs and/or feet due to fluid retention (edema),
Palpitations (fast or irregular heartbeat), irregular heart rhythm (arrhythmia),
Increased blood pressure,
Wheezing or shortness of breath (bronchospasms).