Dysfunctional uterine bleeding: 10 mg twice a day for 5 to 7 days. For continuous treatment, 10 mg b.d. from day 11 to day 25 of the cycle.
Pre-menstrual syndrome: 10 mg b.d. from day 12 to 26 of the cycle. The dosage may be increased if necessary.
Endometriosis: 10 mg two to three times daily from day 5 to 25 of the cycle, or continuously.
Dysmenorrhoea: 10 mg b.d. from day 5 to 25 of the cycle.
Irregular cycles: 10 mg b.d. from day 11 to 25 of the cycle.
Hormone replacement therapy: The standard dose is 10 mg daily for the last 14 days of each 28-day estrogen treatment cycle. The dose may be increased to 10 mg twice daily if either early withdrawal bleeding occurs, or if endometrial biopsy reveals inadequate progestational response. For initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration should be used.
Secondary amenorrhoea: 10 mg b.d. from day 11 to 25
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