PANOM-40
Pantoprazole USP 40 mg Tablet
Pharmacological Class: Proton Pump Inhibitor
Indications:
- Short-term treatment of erosion and ulceration of the esophagus caused by gastro-esophageal reflux disease (GERD).
- Peptic Ulcer Disease
- NSAIDs induced gastritis
- Helicobacter pylori infection
Mode of Action
Pantoprazole binds irreversibly to H+K+ATPase (proton pump) present in the parietal cells, which is the terminal stage in gastric acid secretion. So, pantoprazole suppresses the secretion of acid. As it binds irreversibly to the pumps, new pumps have to be made before acid production can be resumed.
Dosage:
Initial treatment is of 40 mg OD for generally 8 weeks duration for GERD.
